You're free to experiment with whatever settings you want (to see if you get better results). However, these are the results I typically use, you can try starting there:
Sampling Method: Euler A (SGM Uniform)
Sampling Steps: 25, CFG Scale: 4.5
Hires.fix: 4x_foolhardy_Remacri (Upscale by 1.5)
Hires Steps: 15, Hires CFG Scale: 4.5, Denoising Strength: 0.5
Adetailer: face_yolov8n
Best quality images in Portrait dimensions (896x1152, etc)